Epidemiology of HHV-6

77% of humans are exposed to HHV-6B by the age of two and the prevalence of HHV-6 in adults is assumed to be over 90%. After the primary infection, the HHV-6 DNA appears briefly in the serum (and spinal fluid) and then a small amount of virus establishes latency. Small amounts of DNA can be found in the white blood cells and saliva in children and adults at the initial infection, but is only found in serum or plasma (the liquid surrounding the blood cells), during active infection. HHV-6 active infections can persist in the brain tissue long after all traces of the virus have disappeared from the blood (Caserta 2004) and can be found in large quantities in the … Continue reading Epidemiology of HHV-6