Yoshizo Asano, MD, PhD
Yoshizo Asano was a dedicated scientist and physician, friend and mentor. We will always remember his tireless efforts on behalf of patients and the research community.
Educaton & Degrees:
M.D. 1969 - Nagoya University
Ph.D. 1978 - Nagaya University
1979-2010 - Department of Pediatrics, Fujita Health University School of Medicine, Professor and Chair
2010-2016 - Professor for Zambia Project, Research Center for Zoonosis Control, Hokkaido University
Scientific Contributions:
Pathogenesis, diagnosis, prevention, and treatment of viral infections (varicella-zoster virus, HHV-6, and HHV-7) in childhood.
Recipient of the HHV-6 Foundation Dharam Ablashi Lifetime Achievement Award in 2011.
He is co-author of over 120 papers on HHV-6 and HHV-7.
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Virus specific cell-mediated immunity may play a role in controlling reactivated human herpesvirus 6B in patients under measles induced immunosuppression. 2014 Serum biomarker kinetics with three different courses of HHV-6B encephalitis. 2012 Development of quantitative RT-PCR assays for detection of three classes of HHV-6B gene transcripts. 2012 Rhabdomyolysis in an infant with primary human herpesvirus 6 infection. 2012 Development of a human herpesvirus 6 species-specific immunoblotting assay. 2012 Different characteristics of human herpesvirus 6 encephalitis between primary infection and viral reactivation. 2011 Kinetics of cytokine and chemokine responses in patients with primary human herpesvirus 6 infection. 2010 Kinetics of cytokine and chemokine responses in patients with primary human herpesvirus 6 infection. 2011 Direct detection of human herpesvirus 6 DNA in serum by variant specific loop-mediated isothermal amplification in hematopoietic stem cell transplant recipients. 2010 Exanthem subitum-associated encephalitis: nationwide survey in Japan. 2009 Relationship between U83 gene variation in human herpesvirus 6 and secretion of the U83 gene product. 2009 Loop-mediated isothermal amplification for discriminating between human herpesvirus 6 A and B. 2008 Elevated serum cytokine levels are associated with human herpesvirus 6 reactivation in hematopoietic stem cell transplantation recipients. 2008 Human herpesvirus 6 infection in adult living related liver transplant recipients. 2008 Direct detection of human herpesvirus 6 DNA in serum by the loop mediated isothermal amplification method. 2007 Human herpesvirus 6 reactivation and inflammatory cytokine production in patients with drug-induced hypersensitivity syndrome. 2006 Time course characteristics of human herpesvirus 6 specific cellular immune response and natural killer cell activity in patients with exanthema subitum. 2006 Drug-induced hypersensitivity syndrome due to mexiletine hydrochloride associated with reactivation of human herpesvirus 7. 2006 Latent infection of human herpesvirus 7 in CD4(+) T lymphocytes. 2006 Postinfectious myeloradiculoneuropathy with cranial nerve involvements associated with human herpesvirus 7 infection. 2005 Analysis of shedding of 3 beta-herpesviruses in saliva from patients with connective tissue diseases. 2005 In vitro and in vivo analysis of human herpesvirus-6 U90 protein expression. 2005 Human herpesvirus 6 fulminant hepatic failure treated by living donor liver transplantation. 2004 Atypical clinical features of a human herpesvirus-6 infection in a neonate. 2004 Detection of human herpesvirus 7 DNA by loop mediated isothermal amplification. 2004 Rapid diagnosis of human herpesvirus 6 infection by a novel DNA amplification method, loop-mediated isothermal amplification. 2004 Variation of human herpesvirus 7 shedding in saliva. 2003 Human herpesvirus 6 infection of human epidermal cell line: pathogenesis of skin manifestations. 2003 Human herpesvirus 7-associated meningitis and optic neuritis in a patient after allogeneic stem cell transplantation. 2003 Evaluation of active human herpesvirus 6 infection by reverse transcription-PCR. 2003 Serological examination of human herpesvirus 6 and 7 in patients with coronary artery disease. 2002 Reactivation of human herpesvirus 6 and 7 in pregnant women. 2002 Guillain-Barre syndrome after exanthem subitum. 2002 Human herpesvirus 6 viremia in bone marrow transplant recipients: clinical features and risk factors. 2002 Latent infection of human herpesvirus 6 in astrocytoma cell line and alteration of cytokine synthesis. 2002 Influenza encephalopathy associated with infection with human herpesvirus 6 and/or human herpesvirus 7. 2002 Fatal adult case of severe lymphocytopenia associated with reactivation of human herpesvirus 6. 2002 Monitoring of active HHV-6 infection in bone marrow transplant recipients by real time PCR; comparison to detection of viral DNA in plasma by qualitative PCR. 2002 Fatal acute myocarditis in an infant with human herpesvirus 6 infection. 2001 Quantitation of human herpesvirus 6 DNA in infant with exanthem subitum by microplate PCR-hybridization assay. 2001 Correlation between HHV-6 infection and skin rash after allogeneic bone marrow transplantation. 2001 Primary human herpesvirus 6 infection in liver transplant recipients. 2001 Transfer of human herpesvirus 6 and 7 antibodies from mothers to their offspring. 2001 Rapid loss of insulin secretion in a patient with fulminant type 1 diabetes mellitus and carbamazepine hypersensitivity syndrome. 2001 Comparison of specific serological assays for diagnosing human herpesvirus 6 infection after liver transplantation. 2001 Correlation between human herpesvirus 6 and 7 infections after living related liver transplantation. 2001 Monitoring four herpesviruses in unrelated cord blood transplantation. 2000 Human herpesvirus 6 infection after living related liver transplantation. 2000 Invasion by human herpesvirus 6 and human herpesvirus 7 of the central nervous system in patients with neurological signs and symptoms. 2000 Central nervous system complications in human herpesvirus-6 infection. 2000 Clinical characteristics of febrile convulsions during primary HHV-6 infection. 2000 Human herpesvirus 6 latently infects mononuclear cells but not liver tissue. 1999
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