HHV-6 ORF |
CMV ORF |
STAGE |
PROPERTIES |
PROTEINS/MABs |
|---|---|---|---|---|
| DR1 | US22 | |||
| DR6 | US22, transactivator, putative oncogene | |||
| DR7/U1 | SR domain, malignant transforming activity, binds to p53 | |||
| U2 | UL23 | CMV US22 gene family, | ||
| U3 | UL24 | CMV US22 gene family, transactivator | ||
| U4 | UL27 | CMV Maribavir resistance | ||
| U7 | UL28 | CMV US22 gene family | ||
| U10 | dUTPase family | |||
| U11 | UL32 | Antigenic tegument protein | HHV6A p100, HHV-6B p101K | |
| U12 | UL33 | Chemokine G protein-coupled receptor | ||
| U13 | UL34 | CMV: Represses US3 transcription | ||
| U14 | UL25 | CMV UL25 gene family, antigenic tegument protein, binds p53 | ||
| U15 | CMV UL25 gene family | |||
| U17 | UL36 | CMV US22 gene family, tegument protein | ||
| U18 | UL37EX3 | IE-B | IE-B membrane glycoprotein | |
| U19 | UL38 | IE-B | IE-B protein, glycoprotein | |
| U20 | Glycoprotein | Specific to HHV-6/7, Glycoprotein, immunoglobulin structure | ||
| U21 | Glycoprotein | Glycoprotein, downregulates HLA I, specific to HHV-6/7 | ||
| U22 | Glycoprotein | Late | Glycoprotein, specific to HHV-6 | |
| U23 | Glycoprotein | Glycoprotein, specific to HHV-6 | ||
| U24 | Glycoprotein | Glycoprotein | ||
| U25 | UL43 | CMV UL22 gene family, tegument protein | ||
| U26 | Putative | Putative multiple transmembrane protein | ||
| U27 | UL44 | DNA polymerase processivity factor | p41 | |
| U28 | UL45 | Ribonucleotide reducactase large subunit, tegument protein | ||
| U29 | UL46 | Capsid asembly and DNA maturation | ||
| U30 | UL47 | Tegument protein | ||
| U31 | UL48 | Large tegument protein | ||
| U32 | UL48a | Capsid protein, hexon tips | ||
| U33 | UL49 | Virion protein | ||
| U34 | UL50 | Membrane-associated phosphoprotein, | ||
| U35 | UL51 | DNA packaging, terminase component, | ||
| U36 | UL52 | DNA packaging | ||
| U37 | UL53 | Primary envelopment, phosphoprotein | ||
| U38 | UL54 | DNA polymerase | ||
| U39 | UL55 | Glycoprotein B (gB) | gp116 | |
| U40 | UL56 | Transport/capsid assembly (TP) | ||
| U41 | UL57 | Early | Major DNA binding protein (MDBP) | |
| U42 | UL69 | Tegument protein, cell cycle block, transactivator | ||
| U43 | UL70 | DNA helicase/primase complex | ||
| U44 | UL71 | Tegument protein | ||
| U45 | UL72 | dUTPase | ||
| U46 | UL73 | Membrane protein | ||
| U47 | UL74 | Glycoprotein O (gO) | ||
| U48 | UL75 | Glycoprotein H (gH) | gp100 | |
| U49 | UL76 | Putative fusion protein | ||
| U50 | UL77 | DNA packaging | ||
| U51 | UL78 | Early | G-protein-coupled receptor | |
| U52 | UL79 | |||
| U53 | UL80 | Protease, capsid assembly protein | ||
| U54 | UL82/UL83 | Tegument protein, Virion transactivator | ||
| U55 | UL84 | Role in DNA synthesis, dUTPase | ||
| U56 | UL85 | Capsid protein | ||
| U57 | UL86 | Major capsid protein (MCP) | ||
| U58 | UL87 | |||
| U59 | UL88 | Tegument protein | ||
| U61 | ||||
| U62 | UL91 | |||
| U63 | UL92 | |||
| U64 | UL93 | DNA packaging; tegument protein | ||
| U65 | UL94 | Tegument protein | ||
| U66 | UL89 | Terminase component | ||
| U69 | UL97 | Phosphotransferase, Ganciclovir kinase | ||
| U70 | UL98 | Alkaline exonuclease (Exo) | ||
| U71 | UL99 | Myristylated virion protein | ||
| U72 | UL100 | Glycoprotein M (gM) | ||
| U73 | Origin | Origin-binding protein (OBP) | ||
| U74 | UL102 | DNA Helicase-primase complex (HP) | ||
| U75 | UL103 | Tegument protein | ||
| U76 | UL104 | DNA packaging, virion protein | ||
| U77 | UL105 | Helicase-primase complex (HP) | ||
| U79 | UL112/UL113 | Transcriptional activation | ||
| U81 | UL114 | Uracil-DNA glycosylase | ||
| U82 | UL115 | Glycoprotein L (gL) | gp80 | |
| U83 | Secreted | Secreted glycoprotein, CC chemokine | ||
| U85 | UL119 | Glycoprotein | ||
| U86 | UL122 | IE-A | IE-A | |
| U88 | IE-A | IE-A | IE-A | |
| U90 | UL123 | IE-A | IE-A (IE 1), transactivator | |
| U91 | UL124 | IE-A | ||
| U94 | Latency | Parvovirus rep homolog (Rep) | ||
| U95 | CMV US22 gene family | |||
| U100 | Late | Spliced envelope glycoprotein Q, assoc. with lipid rafts | gp82-gp105 |
Sources: Wikpedia, Field’s Virology