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Active ciHHV6 linked to heart failure, a condition treatable by antiviral therapy Berlin Charite study shows heart failure patients with active ciHHV-6 can be treated successfully with antivirals.
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Infants with congenital HHV-6 infection have lower Bayley scores at 12 months ciHHV-6 infants score 4 points lower than controls on the Bayley Mental Development Index
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HHV-6A reactivation in a ciHHV-6A transplant patient with encephalitis Experts emphasize need for larger studies to determine the impact of ciHHV-6 on patient outcomes
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Can a novel free radical scavenger help patients with HHV-6 encephalopathy? Edaravone shows promise for reducing oxidation and neuronal damage in AESD.
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New findings characterize immune response to HHV-6 New details may help advance the field of HHV-6 immunotherapy.
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Featured News

  • Special Issue on Roseoloviruses! Special Issue on Roseoloviruses!
    The December 2014 issue of Current Opinions in Virology features a "Special Section on Roseoloviruses." Top experts in the field contributed a set of 14 reviews that span a wide range of critical topics discussed at the recent June 2014 NIH-sponsored workshop “Roseoloviruses: Unmet needs and research priorities.”
  • Is there a new HHV-6 animal model on the horizon? Is there a new HHV-6 animal model on the horizon?
    Seattle group announces the discovery of novel HHV-6 and HHV-7 homologs in pig-tailed macaques
  • Interview with Michael Boeckh and Joshua Hill on potential risks for ciHHV6 patients undergoing HCT Interview with Michael Boeckh and Joshua Hill on potential risks for ciHHV6 patients undergoing HCT
    The University of Washington and the Fred Hutchinson Cancer Research Center are at the forefront of studying the role of HHV-6 and ciHHV-6 in stem cell transplant patients. We asked their view on the implications immunocompromised patients with integrated HHV-6A reactivating with their own inherited virus.
  • HHV-6 status epilepticus in an immunocompetent adult HHV-6 status epilepticus in an immunocompetent adult
    Immunocompetent adults are not supposed to get HHV-6 encephalitis or status epilepticus (SE) and HHV-6 testing is rarely performed in these patients. A new case report from Baylor suggests that testing for HHV-6 in these patients may be worthwhile.
  • Expert Opinion: Dr. Louis Flamand calls for screening of transplant organs and cells for CIHHV-6 status Expert Opinion: Dr. Louis Flamand calls for screening of transplant organs and cells for CIHHV-6 status
    Dr. Flamand, a professor and molecular virologist at Université Laval in Quebec city, has written an editorial calling for screening of organ donors for ciHHV-6 status and careful monitoring of recipients of ciHHV-6 donor tissues for signs of active HHV-6 infection and HHV-6 antigen-induced immune rejection. Flamand also questions whether solid organs and stem cells derived from persons with ciHHV-6 should be used in transplantation.
  • Conclusive evidence that ciHHV6 activates in vivo Conclusive evidence that ciHHV6 activates in vivo
    The inherited strain of HHV-6A in an immunosuppressed infant activated and caused hemophagocytic syndrome that was responsive to antiviral treatment. The isolated strain matched that of his ciHHV6 father.
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Latest HHV-6 Research

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Repository of Reagents

Reagents for conducting HHV-6 & 7 research are available through the HHV-6 Foundation Repository

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About the Foundation

The HHV-6 Foundation in a non-profit entity founded to encourage scientific exchange between investigators and to provide pilot grants for promising scientific and clinical research on the under- appreciated viruses HHV-6A and HHV-6B. The Foundation sponsors international conferences and supports scientists and clinicians seeking to clarify the role of the two HHV-6 viruses in disease. Since the HHV-6A and HHV-6B can smolder in the brain and other organs without circulating in the peripheral blood or plasma, identifying chronic infection is a challenge. Read More

ciHHV-6 Patient Registry

Except for transplant patients, HHV-6 plasma DNA tests are rarely positive. Any patient testing positive should rule out chromosomally integrated HHV-6, a condition that may be associated with increased HHV-6 reactivation.

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