NEJM HIGHLIGHTS A CASE OF HHV-6 REACTIVATION IN DRESS

In Latest Scientific News by Kristin Loomis

The NEJM rarely covers HHV-6, but did an excellent case history of this patient with HHV-6 reactivation in conjunction with DRESS. The patient was not treated with an antiviral in spite of a plasma HHV-6 DNA load of 112,836, extensive lymphadenopathy, rash and abnormal liver function tests. What did NEJM get wrong? They stated ciHHV6 could be ruled out because a) the viral load was only log 5 on a plasma DNA test and b) the viral load dropped to less than 500 copies/ml. The plasma viral load in a ciHHV-6 patient can fall below 500 copies/ml if the blood is centrifuged within a few hours. On the other hand, ciHHV-6 samples shipped overnight and centrifuged the next day, are …

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HHV-6 small non-coding RNA proposed as an indicator of an early stage of HHV-6 reactivation

In All, Alzheimer's Disease, Latest Scientific News by Kristin Loomis

German investigators have identified a marker for what they believe is the earliest stage of viral reactivation, or “transactivation” marked by transcription of several viral small non-coding RNAs in the absence of detectable viral replication. The group believes that these viral small RNAs could be developed as biomarkers.

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HHV-6 in the news!

In Latest Scientific News by Kristin Loomis

After years of very little interest by the scientific community, there has suddenly been a lot of interest in HHV-6A, which along with HHV-7, appears to be central to the progression of Alzheimer’s disease.