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Does CD134 upregulation explain why HHV-6 reactivates preferentially in DRESS/ DIHS?

In All, Drug Hypersensitivity, Latest Scientific News, Skin Conditions, Transplant Complications by Kristin Loomis

It has long been a mystery why HHV-6 is preferentially reactivated in drug reaction with eosinophilia and systemic symptoms (DRESS), also known as drug induced hypersensitivity syndrome (DIHS). HHV-6 reactivation occurs in over 60% of severe cases and is part of the definition of DIHS in Japan. Investigators in Japan suspect that the explanation may lie with the CD134 receptor on activated CD4 cells.