Levels of HHV-6B and HHV-7 DNA in saliva were higher in people with ME/CFS than in health controls and tended to be higher at times symptoms were worse. Similar correlations were not seen for other human herpesviruses.
Latent HHV-6, mitochondrial fragmentation and a hypometabolic state in ME/CFS patients
A team of virologists and metabolomics specialists collaborated to demonstrate how chromosomally integrated HHV-6 can be stimulated to secrete factors that simultaneously cause mitochondrial fragmentation, a reduction in intracellular ATP reserve and an expanded antiviral defense by their neighboring cells.
Antibodies to herpesvirus dUTPase a potential biomarker for Gulf War Illness and CFS
Antibodies to HHV-6 and VZV dUTPases were significantly elevated in Gulf War Illness patients compared to controls, and EBV dUTPase antibodies were elevated in Chronic Fatigue Syndrome patients.
CFS patients with ciHHV-6 may benefit from antiviral treatment
Researchers at the University Of South Florida’s Morsani College Of Medicine have published findings that suggest ciHHV-6 is the possible cause of some CFS cases
CFS: a herpesvirus infection of the vagus nerve?
A new theory suggests CFS may be the result of a pathological infection of the vagus nerve.
New HHV-6 species-specific serological assay developed
This new assay will hopefully open the door for increased exploration into the seroepidemiology of HHV-6A and HHV-6B infection.
HHV-6 induces oxidative stress and chlamydial persistence
Findings indicate that HHV-6 infection leads to decreased glutathione production, increased oxidative stress, and induces chlamydial persistence during co-infection