• 12th International Conference on HHV-6 & 7 Announced

    The 12th International Conference on HHV-6 & 7 will convene in Japan at the Himeji Culture and Convention Center in March 2025.

  • Co-infection of HHV-6A and EBV results in a 6.7 fold increased risk of developing multiple sclerosis

    The increased risk occurred only in adults who were infected with EBV after their teenage years, and had elevated EBNA-1 antibodies.

  • Metformin reduces HHV-6A replication in T cells by activating AMPK

    Conversely, HHV-6A infection increases viral replication by inhibiting AMPK and enhancing mTOR signaling and glycolysis.

  • Reactivation of a transplant recipient’s iciHHV-6B resulted in an active infection of his donated liver

    Investigators from the University of Helsinki used highly sophisticated techniques to establish that the donor’s integrated virus reactivated and then infected the graft. This thorough investigation highlights the potential pathological impact of iciHHV-6B in transplantation.

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Naesens Presentation

Therapy

The Difficult Path Towards an HHV-6 Therapy

Lieve Naesens, PhD, Laboratory of Virology and Chemotherapy, Rega Institute, KU Leuven, Belgium

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ABOUT THE HHV-6 FOUNDATION

The HHV-6 Foundation in a non-profit entity founded to encourage scientific exchange between investigators and to provide pilot grants for promising scientific and clinical research on the under- appreciated viruses HHV-6A and HHV-6B.

The Foundation sponsors international conferences and supports scientists and clinicians seeking to clarify the role of the two HHV-6 viruses in disease. Since HHV-6A and HHV-6B can smolder in the brain and other organs without circulating in the peripheral blood or plasma, identifying chronic infection is a challenge.

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