HHV-6B is commonly found in the saliva after primary infection, and is passed to infants from family members and caregivers. Little is known about the transmission of HHV-6A since it is generally not found in the saliva. It is known that children do acquire HHV-6A from family members in Africa. One potential route of transmission could be through the nose. Several studies have suggested that HHV-6A could also be transmitted sexually (Chang 1994, Leach 1994).