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Investigators at the Fred Hutchinson Cancer Research Center and University of Washington in Seattle found that HHV-6B in lung fluid of bone marrow transplant recipients with pneumonia is associated with a 2-fold increased risk of death. Importantly, HHV-6B positive patients who were treated with an antiviral had a 60% lower risk of death.
Karolinska Institute researchers developed a novel serological assay to determine that individuals with antibodies to HHV-6A early proteins are more likely to develop MS. HHV-6A antibodies were the highest in the presence of elevated EBV antibodies, suggesting that the two viruses could jointly contribute to the development of MS.
New guidelines from Japan recommend foscarnet as the first-line treatment for HHV-6 encephalitis, with ganciclovir as second choice. They also recommend a combination therapy in severe cases.
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Contributions of neurotropic human herpesviruses herpes simplex virus 1 and human herpesvirus 6 to neurodegenerative disease pathology.
Clinical Significance of HHV-6 Positivity on the FilmArray Meningitis/Encephalitis Multiplex PCR Panel.
Herpesviruses excretion in saliva of pediatric transplant recipients.
Viruses in chronic progressive neurologic disease.
Age-Related Macular Degeneration: A Connection between Human Herpes Virus-6A-Induced CD46 Downregulation and Complement Activation?
Hypothesis: Is there a link between the immune response to HHV-6A infection and the interaction network of the genes encoding the CTSS, PTX3, CHI3L1, Mx1, CXCL16, BIRC3 and BST2 proteins?
Paediatric case series of DRESS and the first reported use of infliximab
Prevalence of salivary human herpesviruses in pediatric multiple sclerosis cases and controls.
Report of a Myocarditis Outbreak among Pediatric Patients: Human Herpesvirus 7 as a Causative Agent?
Non-mumps Viral Parotitis During the 2014-2015 Influenza Season in the United States.
Viral etiology of sporadic cases of parotitis among children in Korea during 2013-2014.
Latent Hepatitis Virus Reactivation Due to Drug Reaction: DRESSed to Kill?
Antibody Cross-Reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6).
Case 5-2018: A 63-Year-Old Man with Confusion after Stem-Cell Transplantation.
Successful treatment and FDG-PET/CT monitoring of HHV-6 encephalitis in a non-neutropenic patient: case report and literature review.
A pediatric case of rhabdomyolysis with acute renal failure due to co-infection with Epstein-Barr virus and Human herpesvirus 6.
Multiple transmissions of chromosomally integrated human herpesvirus-6 in one family.
Human herpesvirus-6 encephalitis following chemotherapy induction for acute myelogenous leukemia.
Stricturing Crohn’s disease-like colitis in a patient treated with belatacept.
Exogenous human herpesvirus 6 reinfection after tumor-infiltrating T-lymphocyte therapy.