Data from a recent report may increasingly argue in favor of using the antiviral known as CMX001 for treatment of HHV-6 infection.
New HHV-6 species-specific serological assay developed
This new assay will hopefully open the door for increased exploration into the seroepidemiology of HHV-6A and HHV-6B infection.
In Memoriam- Caroline B. Hall Young Investigator Award
The HHV-6 Foundation has established an award in memory and honor of Dr. Caroline Breese Hall, a renowned Pediatric Infectious Diseases physician and expert on HHV-6 who passed away in December 2012.
Further characterization of HHV-6B immune response leads to development of virus-specific immunotherapy
A group from Baylor has further characterized the clinical HHV-6B immune response, and is using this new information to develop an enhanced adoptive T cell immunotherapy specific to HHV-6 for HSCT patients.
HHV-6 induces oxidative stress and chlamydial persistence
Findings indicate that HHV-6 infection leads to decreased glutathione production, increased oxidative stress, and induces chlamydial persistence during co-infection
HHV-6 active replication genetically linked to poor treatment response among MS patients
Strong evidence of a genetic link between HHV-6 active replication and poor IFN-B treatment response among multiple sclerosis patients
HHV-6A linked to Thyroiditis, Autoimmune Disease
A group from Italy has linked HHV-6A to Hashimoto’s Thyroiditis, and provides evidence for autoimmune disease associated with HHV-6A and HHV-6B.
Study finds nearly 10% of cord blood transplant patients develop HHV-6 encephalitis
International group calls for routine HHV-6 surveillance in all cases of UCBT
HHV-6 Latent Infection Identified in Patients with Glioma
Investigators from Nanjing Medical University have found HHV-6 latent infection in glioma tissues, and have isolated a strain of HHV-6A from the glioma cyst.
Group identifies HHV-6B-specific CD8+ T Cell response
A new study from the University of Munchen in Munich, Germany, has identified a subset of CD8+ T cells that specifically recognize HHV-6B and not HHV-6A.
Novel multivirus-specific immunotherapy developed as antiviral treatment option for transplant patients.
A novel technique has been developed for the treatment of several viral infections–including HHV-6–following HSCT.
Yale study ties HHV-6 to Hodgkin’s lymphoma
A thorough investigation of the association between HHV-6 and Hodgkin’s lymphoma finds the presence of HHV-6 in a majority of nodular sclerosis cases of HL.
HHV-6A and HHV-6B now recognized as two distinct viruses
The International Committee for Taxonomy of Viruses has made it official. HHV-6A and HHV-6B are two distinct viruses, each with their own characteristics and disease associations.
Febrile Status Epilepticus linked to active HHV-6B and HHV-7 infection
A ten-year NIH-funded study has determined that a third of infants with prolonged seizures and fever suffer from either a new or reactivated roseola virus infection.
HHV-6 causes limbic encephalitis in 10% of cord blood transplant patients.
New study from Harvard finds heightened risk of HHV-6 PALE for UCBT patients.