Researchers discuss the potential mechanisms by which HHV-6A/B may contribute to autoimmune disease
Another fatal case of HHV-6 myocarditis in an immunocompetent adult
Group suggests cardiac magnetic resonance (CMR) may be an important tool for the timely diagnosis
French dermatologists call for antiviral therapy in DRESS
French panel of experts has proposed that DRESS patients be treated with antivirals and/or immunoglobulins.
Human herpesvirus replication is activated by apoptosis
A group led by Steven Zeichner has published evidence that suggests the replication of all human herpesviruses can be activated by apoptosis.
Does HHV-6 cause thyroiditis and autoimmunity in patients with drug hypersensitivity?
Case report describes two cases of DRESS related thyroiditis with very high levels of HHV-6 reactivation that go on to develop autoimmunity.
Humanized mouse model demonstrates HHV-6A infection can cause significant immune dysfunction
Could treatment of HHV-6A co-infections slow AIDS progression?
Preliminary evidence indicates HHV-6B may be involved in the sporadic development of adenomatous GI Polyps
A group from Finland’s Helsinki University Hospital has published preliminary evidence to suggest HHV-6B may be involved in the development of adenomatous gastrointestinal polyps
MCP-1 found elevated in the CSF of patients with HHV-6B encephalopathy
Japanese group identifies several cytokine and chemokine responses associated with HHV-6B encephalopathy.
Study shows HHV-6 reactivation is disproportionately elevated among patients with autoimmune connective tissue disease
New study from Italy indicates that HHV-6 reactivation is selectively increased among patients suffering from autoimmune connective tissue diseases (ACTD).
HHV-6B infection promotes unique pro-inflammatory effects tied to neurocognitive decline and artherosclerosis
HHV-6A and HHV-6B each express distinct chemokines that are uniquely capable of activating key inflammatory cytokines.
Acute hepatitis associated with HHV-6 infection in liver transplant patients
French study suggests HHV-6 is a pathological cause of confluent necrosis.
New HHV-6B specific cellular receptor identified
CD134, a member of the TNF receptor superfamily, has now been shown as a specific entry receptor for HHV-6B.
Reported case of chorea and febrile status epilepticus caused by HHV-6 encephalitis
Case report describes child with multiple episodes of febrile status epilepticus, followed by chorea and developmental regression, caused by human herpes virus-6 encephalitis.
HHV-6 and EBV identified as risk factors in Alzheimer’s Disease
New data suggests HHV-6 and EBV are associated with the development of Alzheimer’s in elderly persons.
Valganciclovir shows promise during first randomized clinical trial for treatment of HHV-6 & EBV in CFS patients
Stanford clinical trial indicates that VGCV may have a clinical benefit among a subset of CFS patients with HHV-6 and EBV infection