Two papers published this month highlight the potential of the new 3rd generation PCR assays in the field of HHV-6 diagnostics.
Understanding the association between ciHHV-6 and HIV disease
HIV+ individuals with ciHHV-6 may experience lower severity HIV disease.
Activation of ciHHV-6 by telomeric circle formation
Additional evidence that shortened telomeres can cause the release and possible activation of integrated HHV-6.
Q & A with Dr. Bhupesh Prusty and Professor Thomas Rudel
Dr. Bhupesh Prusty and Professor Thomas Rudel from Biozentrum University have published several articles on the phenomenon of ciHHV-6 activation including a study on the interaction between Chlamydia infection and ciHHV-6. We interviewed them about the implications of these findings, their current studies, and what lies ahead for this team in the field of ciHHV-6 research.
ciHHV-6 low in Quebec children with ALL and absent in controls
The frequency of ciHHV-6 in the Province of Quebec (Canada) appears to be lower than that observed in US and UK.
CFS patients with ciHHV-6 may benefit from antiviral treatment
Researchers at the University Of South Florida’s Morsani College Of Medicine have published findings that suggest ciHHV-6 is the possible cause of some CFS cases
Chlamydia infection induces activation of ciHHV-6 leading to linear and circular DNA
A laboratory at the University of Wurzburg has published evidence that Chlamydia trachomatis may induce the activation of ciHHV-6.
ciHHV-6 diagnostic test now available
A newly developed assay is now commercially available for clinical diagnosis of chromosomally integrated HHV-6 (ciHHV-6)
Mothers with ciHHV-6 can produce active virus, transmit to children transplacentally
New findings suggest that ciHHV-6 can be reactivated and then acquired transplacentally.
International group of HHV-6 investigators review inherited or “chromosomally integrated” HHV-6 (ciHHV-6)
An international group of HHV-6 experts, investigators and clinicians have published a comprehensive review of chromosomally integrated HHV-6 (ciHHV-6). The article, entitled “Chromosomally Integrated human herpesvirus-6: questions and answers,” is written in response to the widespread confusion in the medical community on how to test or diagnose the condition, as well as how to treat a patient with ciHHV-6 who may or may not have symptoms consistent with HHV-6 reactivation.
Clinical Significance of Pre-Transplant Chromosomally-Integrated HHV-6 in Liver Transplant Recipients
The reactivation of HHV-6 in transplant recipients has long been known to induce clinical complications and poor outcomes following transplantation. However, the clinical relevance of transplant patients with ciHHV-6…